The University of Chicago
Department of Pediatrics, Section of Hematology/Oncology
900 East 57th Street, KCBD 5121
Chicago, IL 60637-1234
Office: (773) 702-5960
Fax: (773) 834 1329
Email: xyang2 at

Xinan Holly Yang, Ph.D.

Research Associate Professor

I am a computational biology researcher with expertise in the design, analysis, and interpretation of the vast amounts of data being generated by biologists and translational scientists.

My innovative work has contributed to advancing translational bioinformatics. I am currently working on topological significance analyses of complex regulatory networks in complex diseases or developmental progresses to facilitate the generation of new hypotheses.


ACADEMIC APPOINTMENTS & TRAINING -- Appreciate all my mentors !

9/1990 – 6/1994 B.S., Radio Techniques Engineering. Southeast University, China
9/1999 – 3/2002 M.S., Biomedical Engineering, Southeast University, China Prof. Xiao Sun
9/2002 – 10/2006 Ph.D., Biomedical Engineering, Southeast University, China; Dept. of Computational Molecular Biology, Max-Planck-Institute for Molecular Genetics, Berlin, Germany Profs. Zuhong Lu;   Rainer Spang
9/2006 – 12/2008 Lecturer, State Key Laboratory of Bioelectronics, Southeast University, China Profs. Zuhong Lu;   Xiao Sun
6/2008 – 3/2010 Post-Doctoral Scholar, Department of Medicine, Section of Genetic Medicine and Center for Biomedical Informatics, The University of Chicago Prof. Yves Lussier
4/2010 – 3/2019 Research Assistant Professor, The University of Chicago Profs. John Cunningham;   Ivan moskowitz;   Yves Lussier
4/2019 – Research Associate Professor, Department of Pediatrics, The University of Chicago   

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TRAINEES -- There are no ordinary students; they are fantastic!

Moses Agustin 6/2026 - 9/2024 2024 Summer Research Fellowship, applying machine learning and AI to biological and health sciences R/Python programming Undergraduate, UofC
Charmi Desai 9/2023 - 6/2024 MS Biomedical Sciences (BMS) program, UofC R/Python programming Video CS Master candidate, UofC
Megan Wei 6/2021 - 4/2022 Bioinfromatics Internship Bioinfromatics Internship MATLAB programming Undergraduate, Johns Hopkins
Arjun Kinstlick 4/2020 - 10/2020 Research Assistant Internship, UofC Upgraded Python2.7 to Python3 for Seq2pathway R package Software Engineering Analyst @ Goldman Sachs
Ieva Tolkaciovaite 4/2020 - 9/2020 Capstone Project Student, UofC, Graham School Capstone - My 1st R and big data project Video MD candidate
Antonio Feliciano 6/2019 - 8/2019 Summer internship, Latin High-school of Chicago Internship experience in data science Video Undergraduate, Stanford
Qier An 4/2019 - 9/2019 Capstone Project Student, UofC, Graham School R package testing and debugging Master candidate, UofC
Biniam Feleke 4/2019 - 9/2019 Capstone Project Student, UofC, Graham School Building Bioconductor Vignette Video Bioinformatics Analyst, Q² Solutions
Yuxi (Jennifer) Sun 2/2019 - 4/2022 Undergraduate volunteer in IT; Micro-Metcalf Program Project, UofC Updating Bioconductor package Video Phd candidate in Economics, Princeton Uni.
Dannie Griggs 2/2019 - 9/2019 BSCD Undergraduate fellow, UofC Scientific Editting, scRNA-seq data Analysis
Lijia (Leah) Wang 6/2018 - 9/2018 BSCD Undergraduate fellow, UofC Learning R as a beginner Video Master program in Biostatistics, U Michigan
Xiangying Sun 1/2018 - 6/2018 IT Programmer, UofC Chromatin-enriched nuclear RNA-seq analysis Tuxedo-ch Bioinformatics Scientist, Thermo Fisher
Zhezhen Wang 12/2016 - 10/2019 Bioinformatican, UofC, Pediatrics BioTIP R package Bioinformatican, UofC
Carlos Perez-Cervantes 8/2016 - 8/2017 Bioinformatican, UofC, Pediatrics Sequencing data analysis PhD candidate in Genetics
Bin Wang 2/2014 - 7/2015 Programmer, UofC, Pediatrics Seq2pathway R package Senior Analyst, China Telecom Americas

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2003-2005 German Academic Exchange Service (DAAD) Scholarship
2006-2007 Guiping Zhang Award for Excellence in Scientific Research and Teaching, Southeast University, China
The Best Paper Award in 2007 International Conference on Life System Modeling and Simulation sponsored by IEEE, 9/2007, Shanghai, China
2009 The Outstanding Paper in 2009 AMIA Summit on Translational Bioinformatics, March 2009, San Francisco, USA
2010 The Outstanding Paper in 2010 AMIA Summit on Translational Bioinformatics, March 2010, San Francisco, USA


Bio-informatics Tools

Invited Speaking & Reviews


Professional Societies & Services

Scholarship Statement

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