MIME-Version: 1.0 Content-Type: multipart/related; boundary="----=_NextPart_01CBCDBF.FD4890B0" This document is a Single File Web Page, also known as a Web Archive file. If you are seeing this message, your browser or editor doesn't support Web Archive files. Please download a browser that supports Web Archive, such as Microsoft Internet Explorer. ------=_NextPart_01CBCDBF.FD4890B0 Content-Location: file:///C:/F057B2D4/publist.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" Kang Publications

Representative recent publications wi= th PDF file links:

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Mechanisms of Dopaminergic Therapy = in PD

Ding Y, W= on L, Britt JP, Lim SAO, McGehee DS, Kan= g UJ.  Enhanced striatal cholinergic neur= onal activity mediates L-DOPA induced dyskinesia in parkinsonian mice.  Proc Natl Acad = Sci U S A. 2010 Dec 27. [Epub ahead of print] PMID: 21187382 <= span style=3D'color:windowtext'>[pdf]

Beeler JA, Cao ZFH, Kheribek MA, Ding Y, Koranda J, Mura= kami M, Kang UJ, Zhuang X.  Dopamine-dependent motor learning: insight into levodopa’s long duration response.  Ann Neurol 2010;67:639-647. PMID: 20437561 [pdf]

Ding Y, Restrepo J, Won L, Hwang D-Y, Kim K-S, Kang UJ.  Chronic 3, 4-dihydroxyphenylalanine treatment induces dyskinesia in aphakia mice, a novel genetic model of Parkinson's Disease. Neurobiology of Disease 2007; 27:11-23. [pdf]

Hwang D-Y, Ardayfio P, Kang UJ, Semina EV, Kim K-S.  A selective loss of the dopaminergic neurons in the substantia nigra of the Ptx3-mutated aphakia= mice. Brain Res Mol Brain Res. 2003; 114(2):123-31. [pdf]

Chang JW, Wachtel SR, Young D, Kang UJ.  Biochemic= al and anatomical characterization of forepaw adjusting steps in a rat model of Parkinson’s disease: studies on medial forebrain bundle and striatal lesions. Neuroscience 1999; 88:617-628. [pdf]

Lee EA, Kim YS, Lee W= Y, Kang UJ.  The effec= ts of chronic L-DOPA therapy on pharmacodynamic parameters in a rat model of motor response fluctuations. Exp Neurol 2003; 184(1):304-12. [pdf]

Meredith = GE, Kang UJ.  Behavioral models of Parkinson's d= isease in rodents: A new look at  an = old problem. Mov Disord 2006; 21(10):1595-606.

 

Mechanisms of Neurodegeneration in = PD

Lin W, Kang UJ.  Structural determinant of PINK1 to= pology and dual subcellular distribution.  BMC Cell Biology 2010:11;90 PMID: 21092208 [pdf]<= /p>

Lin W, Kang UJ.  Characterization of PINK1 processing, stability, and subcellular localization. J Neurochem 2= 008 ;106 (1):464-74. [pdf]=

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Yang W, Chen L, Ding Y, Zhuang X, Kang UJ.  Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice.  Human Mol Genet 2007; 16:2900-2910. [pdf]=

Chen L, Cagniard B, Mathews T, Jones S, Koh HC, Carvey PM, Ling Z, Kang UJ, Zhuang X. Dopaminergic dysfunction and age-dependent m= otor deficits in DJ-1 null mice. J Biol Chem 2005; 280(22):21418-26. [pdf]

 

Chen L, D= ing Y, Cagniard B, Van Laar A, Mortimer A, Chi W, Tian N, Hastings, Kang UJ, Zhuang X. Unregulated in= crease of cytosolic dopamine causes neurodegeneration in mice. J Neurosci 2008; 28:425-433. [p= df]

Kweon GR,= Marks JD, Krencik R, Leung EH, Hyland K, Schumacker PT, Kang UJ.  <= span style=3D'mso-bidi-font-size:12.0pt;font-family:"Times New Roman";mso-fareas= t-font-family: Batang;mso-fareast-language:KO'>Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells.  J Biol Chem 2004; 279(50):51783-51= 79. [pdf]

Nakamura = K, Bindokas V, Elas M, Milstien S, Kowlessur D, Marks J, Halpern H, Kang UJ. Tetrahydrobiopterin scav= enges superoxide in dopaminergic neurons. J Biol Chem 2001 276(37):34402-7. [pdf]

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Biomarkers in PD:

Shi M, Br= adner J, Hancock AM, Chung KA, Quinn JF, Peskind ER, Galasko D Jankovic J, Zabeti= an CP, Kim HM, Leverenz JB, Montine TJ, Ginghina C, Kang UJ, Cain KC, Aasly J, Goldstein DS, Zhang J.  Cerebrospinal fluid biomarkers for Parkinson’s disease biomarkers and progression.  Ann Neurol (in press)

Hong Z, S= hi M, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian AP, Leverenz JB, Baird G, Montine TJ, Hancock AM, Hwang H, Pan C, Bradner J, Kang UJ, Jensen PH, Zhang Z.  DJ-1 and a-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease. Brain 2010<= span class=3Dsrc1>;133(Pt 3):713-26.  PMID: 20157014 [pdf]=

Kang UJ.&nb= sp; Guest Editor, Biomarkers in Neuropsychiatric Diseases. Neurobiology = of Disease Special Issue 2009;35(2):115-6. PMID: 19464368 [pdf]

Potashkin JA, Kang UJ, Loomis, PA, Jodelka, FD, Ding Y, Me= redith GE.  MPTP administration in mi= ce changes the ratio of splice isoforms of fosB and rgs9.  Brain Res 2007; 1182:1-10. [pdf]=

 

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updated on 2/16/2011

 

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