Mark F. Ciaccio
Doctoral Candidate
Laboratory of Dr. Richard B. Jones, The University of Chicago
Affiliations:
The Ben May Institute for Cancer ResearchThe Institute for Genomics & Systems Biology
Committee on Cellular and Molecular Physiology
The Center for Systems Biology of Oxygen Sensing
Contact Information:
Mark Ciaccio, Jones GroupKnapp Center for Biomedical Discovery, Room 10240D
900 East 57th St.
Chicago, IL 60637
Home Phone: (773) 454-2600
Email: ciaccio@uchicago.edu
Objective:
To obtain a full-time position with a focus in Systems Biology/Technology Development, specifically withthe intention of expanding the use of the Microwestern Array to diverse fields of biology.
Research:
My current project has been developing the Microwestern Array (MWA) and expanding its capabilities.Specifically I have been using the MWA to characterize phosphorylation cascades and model cell
phenotype as a function of short-term phosphorylation kinetics of signaling molecules.
Publications:
Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits.Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF, Gat-Viks I, Tonti E, Degrace MM,
Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Andersen MS, Root DE, von Andrian U,
Jones RB, Park H, Carr SA, Regev A, Amit I, Hacohen N.
Cell. 2011 Nov 11;147(4):853-67.
PMID: 22078882
Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin.
Liu J, Kuo WL, Seiwert TY, Lingen M, Ciaccio MF, Jones RB, Rosner MR, Cohen EE.
Head Neck. 2011 Mar 24. Epub.
PMID: 21438065
Systems analysis of EGF receptor signaling dynamics with microwestern arrays.
Ciaccio MF, Wagner JP, Chuu CP, Lauffenburger DA, Jones RB.
Nat Methods. 2010 Feb;7(2):148-55. Epub 2010 Jan 24.
PMID: 20101245
Systems-level analysis of ErbB4 signaling in breast cancer: a laboratory to clinical perspective.
Chuu CP, Chen RY, Barkinge JL, Ciaccio MF, Jones RB.
Mol Cancer Res. 2008 Jun;6(6):885-91. Review.
PMID: 18567793
Cytosolic prion protein toxicity is independent of cellular prion protein expression and prion propagation.
Norstrom EM, Ciaccio MF, Rassbach B, Wollmann R, Mastrianni JA.
J Virol. 2007 Mar;81(6):2831-7. Epub 2006 Dec 20.
PMID: 17182694
Patents:
Title: Methods and Compositions related to Microscale Sample Processing and EvaluationInventors: Richard Jones and Mark Ciaccio
Publication Date: 11.06.2009
Publication Number: WO/2009/073632
Teaching Experience:
Protein Post-Translational Modifications, LecturerUniversity of Chicago
Spring Q 2010, 2011
Mentors: Richard Jones, Piers Nash, Yingming Zhao
Cancer Biology IV: Frontiers in Cancer biology, Lecturer
University of Chicago
Spring Q 2011
Mentors: Mark Lingen, Carrie Rinker-Schaeffer, Richard Jones
Relay for Life
Guest Research Speaker
Kankakee, IL June 2010, 2011
Fundamentals of Molecular Biology, Teaching Assistant
University of Chicago, Spring 2008
Mentors: Dr. Ursula Storb, Dr. Jon Staley
Teaching Assistantship Training, Student
University of Chicago Graduate Class, Winter 2008
Mentor: Dr. Nancy Schwartz
English as a Second Language, Teacher
St. Teresa Parish, Kankakee, IL 2001-2003
Mentor: Sr. Josephine Ciaccio
*Examples of personal training lectures available at: http://www.youtube.com/user/RichardBJonesLab
Education:
University of Chicago (Sept. 2006 - Current)Biological Sciences Division
Committee on Cellular and Molecular Physiology
Doctoral Program
University of Notre Dame (1998-2002)
Notre Dame, IN
College of Engineering
B.S. Biochemical Engineering
Illinois Mathematics and Science Academy (1995-1998)
Aurora, IL
College Preparatory Secondary Education