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PROGRAM OPTIMIZE

Andrew Abbott

Biological Software Currently Available

I am in the process of testing these, and so cannot give final advice on them. Where I know them I give addresses, computer info, etc. Most important biological sequencing programs are now shareware, in contrast to the situation until quite recently.

ATBE
approximate tree matching, Wang, Jeong, Zhang, Shasha NYU dept computer science Vingron/Argos alignment of distant relations, Multiple alignment VINGRON@embl.bitnet
SOMAP
Parry-Smith and Attwood, CABIOS 7:233-35. multiple alignment VAX VMS, interactive symbolic manipulation program (like Explore) Astbury Dept of Biophysics and Genetics, Univ of Leeds, England
ADSP
Parry-Smith and Attwood, CABIOS 8:451-459 front end for SOMAP, mostly of biological use
MASH
Chappey et al. CABIOS 7:195-202 - multiple alignment in PASCAL for DOS or MAC.
MUSEQUAL
Berger and Munson CABIOS 7:473-481 iterative mult alignment PC based with environment.
MACAW
Schuler, Altshcul, Lipman, Proteins 9:180-190 multiple alignment, up to 16 seqs, Windows 3.0 National Center for Biotechnol Information ncbi.nlm.nih.gov
FASTA
Pearson and Lipman, PNAS 85:2444-8. database search for sequences, William Pearson, wrp@virginia.bitnet
MSA
Lipman, Altschul, Kececioglu PMAS 86:4412-4415. multiple alignment, (MCBI?)
Alexandrov
Alexandrov CABIOS 8:339-345 local multiple alignment.
MATCHBOX
Depiereux and Feytmans CABIOS 8:501-509 multiple alignment, up to 200 sequences, 100,000 elements (!) EDEPIEREUX@bnandp51.bitnet
SERPENT
Various authors CABIOS 8:295-296 This is the SPSS of sequence programs, but designed for biological inputs VMS, Unix, soon to be commercial
CLUSTAL V
Higgins, Bleasby, and Fuchs - Multiple Sequence Alignment in C. EMBL file server (Netserv@embl.Heidelberg.de)
Boguski, Hardison, Schwartz, Miller
Multiple alignment toolkit C for Unix, but translatable. groucho.cs.psu.edu
Preliminary Notes Back to Top Introduction to Optimize Algorithm

Contact Information:
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Email to: a-abbott@uchicago.edu